StoppingDoseStabilized

StoppingDoseStabilized is the class for stopping when the next best dose has stabilized. Stabilization occurs when the current next best dose is the same as the dose administered to each of the most recent consecutive nCohorts cohorts.

For combination trials, both dose components must be the same.

Usage

StoppingDoseStabilized(nCohorts = 1L, report_label = NA_character_)

.DefaultStoppingDoseStabilized()

Arguments

nCohorts

(number)
see slot definition.

report_label

(string or NA)
see slot definition.

Slots

nCohorts

(number)
number of consecutive cohorts required to have received the current next best dose.

Note

Typically, end users will not use the .DefaultStoppingDoseStabilized() function.

Examples

# Stop when the next best dose has remained unchanged for three consecutive
# cohorts.
my_stopping <- StoppingDoseStabilized(nCohorts = 3)