Helper for Evaluating the True Toxicity Probability at a Dose Combination

Evaluates the true toxicity probability at a given dose combination using the provided truth function. The truth function can be flexible in how it accepts the dose combination as input, and this helper tries different ways to call it in order to extract the toxicity probability.

Usage

h_eval_combo_truth(truth, dose_pair, ...)

Arguments

truth

(function)
optional function mapping a dose combination to a toxicity probability. It can accept one argument (length-2 numeric vector or one-row matrix) or two numeric arguments (drug1, drug2).

dose_pair

(numeric)
a length-2 numeric vector representing the dose combination for drug1 and drug2.

...

additional arguments passed to truth.

Value

A numeric value representing the true toxicity probability at the given dose combination, or NA_real_ if it cannot be evaluated.