ComboSimulations

This class captures trial simulations from two-drug combination designs (DesignCombo).

It is intentionally separate from Simulations because DataCombo is not a subclass of Data, and final recommendations are dose combinations.

Usage

ComboSimulations(
  data,
  doses,
  fit,
  stop_reasons,
  stop_report,
  additional_stats,
  seed
)

.DefaultComboSimulations()

Arguments

data

(list) see slot definition.

doses

(matrix) see slot definition.

fit

(list) see slot definition.

stop_reasons

(list) see slot definition.

stop_report

(matrix) see slot definition.

additional_stats

(list) see slot definition.

seed

(integer) see slot definition.

Slots

data

(list) produced DataCombo objects.

doses

(matrix) final recommended dose combinations; one row per simulation run and two columns (one per drug).

fit

(list) final fitted toxicity surfaces for each simulation run.

stop_reasons

(list) stopping reasons for each simulation run.

stop_report

(matrix) matrix of stopping rule outcomes.

additional_stats

(list) list of additional statistical summary values.

seed

(integer) random generator state before starting the simulation.

Note

Typically, end users will not use the .DefaultComboSimulations() function.